AdvoCare Science

AdvoCare relies on the latest scientific knowledge and highest quality ingredients to create safe and effective products. The AdvoCare Science team includes Doctors dedicated to product research & development as well as training and education for AdvoCare Independent Distributors. The science behind AdvoCare products helps improve lives through superior nutrition and wellness.

Scientific & Medical Advisory Board

Highly regarded and recognized in their areas of expertise, members of the AdvoCare Scientific & Medical Advisory Board use their knowledge and experience in the fields of medicine, nutrition and science to ensure that all AdvoCare products are formulated with the highest quality ingredients based on the latest scientific research.
Stanley Dudrick
M.D., F.A.C.S.
William Kraemer
Kenneth Goldberg
Carl Keen
Leanne Redman
Jose Pimiento
Gail Cresci
Ph.D., R.D., L.D.
Jeffrey Blumberg

Sports Advisory Council

The AdvoCare Sports Advisory Council includes many of the top strength and conditioning coaches and athletic trainers in the country. These experts consult with AdvoCare on issues relating to current and future product development – helping to ensure that AdvoCare stands for innovation and excellence through products that give athletes and performers a competitive edge. They also exchange information on a variety of topics relating to the use of nutritional supplements in the training of athletes and rehabilitation of athletic injuries.
Dean Miller
Council Chair, Associate Head Athletic Trainer, Olympic sports, Rice University
Mark Mauldin
Director of Executive Health for Hendrick Motorsports
Todd Miller, Ph.D.
Associate Professor of Exercise Science at George Washington University School of PHHS
Jerry Punch
Physician of Emergency Medicine and Sports Commentator
Erik Korem
High Performance Coach for University of Kentucky Football
Murphy Grant
Assistant Athletic Director Sports Medicine at the University of Kansas Athletics
Jennifer Jones
Director of Player Development for Women's Basketball at Texas A&M University
Kevin Yoxall
Strength and Conditioning Coach for football at Rice University
Gene Coleman, Ed.D.
Strength and Conditioning Consultant, Professional Baseball
Ivan Lewis
Head Strength and Conditioning Coach for the University of Southern California
Eric Lichter
Strength and Conditioning Specialist for World-Class Athletes
John McBride
Strength and Conditioning Specialist for World-Class Athletes

Quality & Safety

Based on proven and effective science and nutrition, AdvoCare product ingredients are specifically chosen for quality and purity from reputable suppliers that meet the AdvoCare standard of excellence. The vitamins and minerals used in AdvoCare formulas are pharmaceutical or USP grade, with each lot tested for purity and potency. Manufacturing is done in GMP (Good Manufacturing Practice) compliant facilities, with exemplary quality control and quality assurance programs.

AdvoCare is a proud member of the Council for Responsible Nutrition.

Informed-Choice Certification

AdvoCare has formed a strategic alliance with Informed-Choice to certify the products that carry the Informed-Choice logo are banned substance free. AdvoCare values its relationships with the athletic community. With testing on the rise for performance-enhancing substances, both at the amateur and professional levels, this alliance allows athletes to make informed choices about what they put into their bodies. Informed-Choice has specialized anti-doping experience. Their WADA (World Anti-Doping Agency) experienced laboratory adheres to standards for sports supplements and has analyzed more samples for banned substances than any other lab in the world. The AdvoCare program exceeds industry requirements and is key to opening doors to new business.

Banned substance free certification positions AdvoCare as a leader in the sports performance and nutrition industries. The Informed-Choice certification program fosters business growth, adding a layer of credibility for AdvoCare and its Distributors.

Informed-Choice Program Facts
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Top 10 FAQs

  • What AdvoCare® products may I take with medications I am taking?

    As a dietary supplement company, AdvoCare® provides nutritional guidance. AdvoCare does not provide medical advice or make medical claims regarding our products. Before using any AdvoCare products consult your healthcare professional for advice on drug-nutrient interactions or general discussions on herbal or dietary supplements and your health plan. For example, it may be advisable to take medications several hours after consuming the AdvoCare Fiber Drink to help ensure optimal intestinal absorption of medications. Consult your healthcare professional with any questions and for recommendations tailored to your individual situation. †

    † This information is not intended as a substitute for the advice of a healthcare provider.

  • Do any AdvoCare® products interfere with medications?

    Absorption of pharmaceutical drugs, especially high potency low dose drugs such as oral contraceptives, steroidal hormones (hormone replacement therapy), thyroid medications and anticoagulants, may be influenced by certain dietary ingredients such as fiber and tea. Before taking any AdvoCare products consult your healthcare professional for advice regarding potential drug-nutrient interactions and dietary supplements that may be appropriate for your use.†

    † This information is not intended as a substitute for the advice of a physician.

  • Is the 24-Day Challenge™ right for everyone?

    Many individuals are able to successfully use all products in the 24-Day Challenge bundle. However, all products in the bundle may not be suitable for every person. The chance of intolerance can increase with multiple-component product bundles such as the 24-Day Challenge which is comprised of Citrus Herbal Cleanse, MNS®, Meal Replacement Shakes, AdvoCare Spark® and OmegaPlex®.

    There are several groups of individuals for whom the Herbal Cleanse system may not be appropriate. One group may include individuals taking selected pharmaceutical medications. Certain ingredients in Herbal Cleanse tablets and in Citrus Fiber Drink, two components of the Citrus Herbal Cleanse system, may decrease GI transit time and thereby potentially impact drug absorption. It is very important for individuals who take medications to consult their healthcare professionals before using Herbal Cleanse and other AdvoCare products.

    Additionally, Herbal Cleanse may not be suitable for persons with inflammatory gastrointestinal conditions which include but may not be limited to irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). The most common IBD disorders are Crohn's disease and ulcerative colitis. These individuals are sometimes counseled to avoid foods and supplements that are acidic, neuroactive or irritating. AdvoCare Spark, AdvoCare Slam®, MNS, AdvoCare Slim® and Herbal Cleanse are products that may not be suitable for this group of individuals. Please consult your healthcare professional with questions.

    Persons who have an allergy to chrysanthemums, marigolds, ragweed or daisies may be sensitive to ingredients in Herbal Cleanse tablets.

    An alternative to the 24-Day Challenge bundle could include beginning with ProBiotic Restore® Ultra, and then sequentially adding an MNS system, Catalyst™, OmegaPlex, ThermoPlus™, Carb-Ease™ Plus; LeptiLean™ and Spark as needed.†

    †This information is not intended as a substitute for the advice of a healthcare provider.

  • Are any AdvoCare® products appropriate for individuals who are gluten intolerant?

    AdvoCare® products are not produced at certified gluten-free manufacturing facilities. Therefore, we do not certify any AdvoCare products as gluten-free. Individuals who have celiac disease and are gluten-intolerant are advised to consult their healthcare providers regarding AdvoCare products that may be suitable for their use.

  • What AdvoCare® products may I take if I'm pregnant?
  • At what age may I take AdvoCare® products?
  • What is sucralose? Is it safe?

    Sucralose is a sweetener made from table sugar (sucrose) by chlorinating it in three positions on the molecule. This provides a substance which is approximately 600 times sweeter than sucrose and is very poorly absorbed. Therefore, the body does not metabolize it for energy, and only a small amount is needed to effectively sweeten a substance.

    Sucralose has the closest sweetness profile to sucrose, the “gold standard of sweeteners”. It also has exceedingly good solubility and stability properties, making it an excellent choice among non-nutritive sweeteners.

    Sucralose has over a twenty-year history of safe and effective use. It carries no warning from the Food and Drug Administration (FDA) and is approved by the FDA as well as the World Health Organization Expert Committee on Food Additives. It is approved by food and health agencies of over 40 countries. It can be used by pregnant and nursing women since very little is absorbed. Thousands of food and beverage products around the world contain sucralose. AdvoCare® is not aware of any peer-reviewed human research studies published in reputable, well-recognized scientific journals demonstrating toxic or adverse effects.

    The scientific consensus of over 200 research articles affirms the safety of sucralose. The research studies which have been conducted to investigate the safety of sucralose have demonstrated no effects on organs, growth weight, blood chemistry or fertility, and sucralose is not carcinogenic, teratogenic or mutagenic. Sucralose does not produce diarrhea, affect the immune system, alter hormonal systems, cause headaches, produce fatigue or skin conditions. In well-controlled studies, no adverse effects have been found.

    The small amount of chlorine present on the sucrose molecule is a tiny fraction of the amount of chlorine already present in our stomachs in the form of hydrochloric acid which aids digestion. Furthermore, the amount of chlorine present is an even smaller fraction of the amount consumed daily in the form of table salt (sodium chloride).

    There are a number of prominent websites that contain extensive amounts of misinformation regarding sucralose and other substances. The information provided is not based on sound scientific studies. All of the information on these websites is anecdotal and has never been published in any reputable journal, does not involve any reputable research studies, and has never been demonstrated in research studies. Furthermore, the websites reference each other in an effort to create credibility.

    AdvoCare does not use products that are not demonstrated to be safe and well studied. AdvoCare does not use any ingredient deemed to be unsafe or harmful based on sound scientific evidence.

  • What sweeteners does AdvoCare® use in its products?

    There are approximately 30 sweeteners approved by the FDA for human consumption that are deemed to be safe and effective when used appropriately. Sweeteners can be grouped into two categories. Nutritive sweeteners supply calories (energy), bulk, texture, and adhesion. Non-nutritive sweeteners, or as sometimes called "sugar substitutes", do not contribute calories and are non-bulking. FDA-approved non-nutritive sweeteners include sucralose, Acesulfame-K, aspartame, neotame, saccharin and rebaudioside A (reb A).

    A more detailed discussion of sweeteners, a comparison of sweetener characteristics, reviews of the safety and efficacy of sweeteners, and a brief summary of sucralose and fructose are presented in the attached PowerPoint presentation.

    Click here for the Sweetener PDF document

  • What AdvoCare® products may be taken if someone has Inflammatory Bowel Disease (IBD)?

    Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition usually of unknown origin associated with impaired absorption of nutrients from the intestinal tract. Impaired absorption of nutrients is a common characteristic and symptoms may include altered bowel habits, abdominal pain, gas and flatulence. The two main forms of IBD are Crohn's Disease and ulcerative colitis.

    AdvoCare does not make medical claims regarding dietary supplements and does not treat medical conditions. Please consult your healthcare provider for determinations of product suitability. A number of AdvoCare products may be considered by individuals with IBD which may help support and maintain normal gastrointestinal health and aid in overall wellness.

    For excellent core nutrition, CorePlex® can be used.* One CorePlex tablet may be taken with each meal or CorePlex® Chewable tablets may be used since the tablets are chewed and can be readily absorbed. Several products which may help maintain and improve the health of the gastrointestinal tract include ProBiotic Restore™ Ultra, Digest-Ease™, OmegaPlex®, AdvoCare BioTools™ and Amplify A.T.*

    Meal Replacement Shakes provide excellent nutrition, are gentle on the stomach and are readily absorbed.* Another product which is very helpful for overall health is Calcium Plus.* This product provides a bioavailable source of essential minerals and vitamins. For added energy, AdvoCare® Oasis™ is an excellent product that may help with stress management and helps support the immune system.* V16® Energy Drink may also be appropriate.

    In general, individuals with IBD may be counseled to avoid foods and supplements that are spicy, acidic, stimulating, neuroactive, or irritating. Foods and beverages that may be in this category include chocolate, coffee, alcohol, carbonated beverages, milk products, and fatty and fried foods. AdvoCare products which might be avoided include AdvoCare Spark®, AdvoCare Slam®, AdvoCare Slim®, Herbal Cleanse and the MNS® Systems.†

    * This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

    † This information is not intended as a substitute for the advice of a physician.

  • Can AdvoCare® tablets be chewed or crushed if someone is unable to swallow them?

    Those with difficulty swallowing may chew or crush most AdvoCare┬« caplets and tablets. One exception is ActoTherm SR, the thermogenic component in the first color packet of the MNS® Max 3 strip pack. Since the ActoTherm SR caplet is formulated using sustained-release technology, chewing or crushing the caplet interferes with the extended-release mechanism and results in more rapid release of the ingredients. Capsules may be opened and sprinkled on food.