The science
behind the products

AdvoCare Science

AdvoCare relies on the latest scientific knowledge and highest quality ingredients to create safe and effective products. The AdvoCare Science team includes Doctors dedicated to product research & development as well as training and education for AdvoCare Independent Distributors. The science behind AdvoCare products helps improve lives through superior nutrition and wellness.

Scientific & Medical Advisory Board

Highly regarded and recognized in their areas of expertise, members of the AdvoCare Scientific & Medical Advisory Board use their knowledge and experience in the fields of medicine, nutrition and science to ensure that all AdvoCare products are formulated with the highest quality ingredients based on the latest scientific research.
Stanley Dudrick
M.D., F.A.C.S.
William Kraemer
Kenneth Goldberg
Carl Keen
Leanne Redman
Jose Pimiento
Gail Cresci
Ph.D., R.D., L.D.
Jeffrey Blumberg

Sports Advisory Council

The AdvoCare Sports Advisory Council includes many of the top strength and conditioning coaches and athletic trainers in the country. These experts consult with AdvoCare on issues relating to current and future product development – helping to ensure that AdvoCare stands for innovation and excellence through products that give athletes and performers a competitive edge. They also exchange information on a variety of topics relating to the use of nutritional supplements in the training of athletes and rehabilitation of athletic injuries.
Dean Miller
Council Chair, Associate Head Athletic Trainer, Olympic sports, Rice University
Mark Mauldin
Director of Executive Health for Hendrick Motorsports
Todd Miller, Ph.D.
Associate Professor of Exercise Science at George Washington University School of PHHS
Jerry Punch
Physician of Emergency Medicine and Sports Commentator
Erik Korem
High Performance Coach for University of Kentucky Football
Murphy Grant
Assistant Athletic Director Sports Medicine at the University of Kansas Athletics
Jennifer Jones
Director of Player Development for Women's Basketball at Texas A&M University
Kevin Yoxall
Strength and Conditioning Coach for football at Rice University
Gene Coleman, Ed.D.
Strength and Conditioning Consultant, Professional Baseball
Ivan Lewis
Head Strength and Conditioning Coach for the University of Southern California
Eric Lichter
Strength and Conditioning Specialist for World-Class Athletes
John McBride
Strength and Conditioning Specialist for World-Class Athletes

Quality & Safety

Based on proven and effective science and nutrition, AdvoCare product ingredients are specifically chosen for quality and purity from reputable suppliers that meet the AdvoCare standard of excellence. The vitamins and minerals used in AdvoCare formulas are pharmaceutical or USP grade, with each lot tested for purity and potency. Manufacturing is done in GMP (Good Manufacturing Practice) compliant facilities, with exemplary quality control and quality assurance programs.

AdvoCare is committed to conducting business only with vendors who adhere to the highest ethical standards and who comply with laws and regulations applicable to their business. AdvoCare has undertaken actions and implemented processes to ensure that the services and materials provided to AdvoCare meet this commitment. Click here for more.

AdvoCare is a proud member of the Council for Responsible Nutrition.

Informed-Choice Certification

AdvoCare has formed a strategic alliance with Informed-Choice to certify the products that carry the Informed-Choice logo are banned substance free. AdvoCare values its relationships with the athletic community. With testing on the rise for performance-enhancing substances, both at the amateur and professional levels, this alliance allows athletes to make informed choices about what they put into their bodies. Informed-Choice has specialized anti-doping experience. Their WADA (World Anti-Doping Agency) experienced laboratory adheres to standards for sports supplements and has analyzed more samples for banned substances than any other lab in the world. The AdvoCare program exceeds industry requirements and is key to opening doors to new business.

Banned substance free certification positions AdvoCare as a leader in the sports performance and nutrition industries. The Informed-Choice certification program fosters business growth, adding a layer of credibility for AdvoCare and its Distributors. Click here for more.

AdvoCare Products
Certified Banned-Substance Free by INFORMED-CHOICE

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Top 10 FAQs

  • Do any AdvoCare® products interfere with medications?

    Absorption of pharmaceutical drugs, especially high potency, low dose drugs such as oral contraceptives, steroidal hormones (hormone replacement therapy), thyroid medications and anticoagulants, may be influenced by certain dietary ingredients such as fiber and tea. Before taking any AdvoCare products, consult your healthcare professional for advice regarding potential drug-nutrient interactions and dietary supplements that may be appropriate for your use.†

    † This information is not intended as a substitute for the advice of a physician.

  • Is the 24-Day Challenge® right for everyone?

    Thousands of people have had success with the 24-Day Challenge. However, there are some products in the 24-Day Challenge that may not be suitable for every individual. This is why it is very important to check with your healthcare professional before beginning any AdvoCare® regimen.

    For example, individuals who take medications or those who have gastrointestinal conditions could have intolerance problems during the Cleanse Phase.

    An alternative to the 24-Day Challenge could include beginning with ProBiotic Restore™ Ultra, and then sequentially adding an MNS® system, Catalyst™, OmegaPlex®, ThermoPlus®, Carb-Ease® Plus; LeptiLean® and AdvoCare Spark® as needed. †

    †This information is not intended as a substitute for the advice of a healthcare provider.

  • Are any AdvoCare® products appropriate for individuals who are gluten intolerant?

    AdvoCare® products are not produced at certified gluten-free manufacturing facilities. Therefore, we do not certify any AdvoCare products as gluten-free. Individuals who have celiac disease and/or are gluten-intolerant are advised to consult their healthcare professional regarding AdvoCare products that may be suitable for their use.

  • Can I take AdvoCare® products if I am pregnant or nursing?

    Click here for Product Age, Pregnancy and Nursing Indications. AdvoCare does not currently have or encourage a 24-Day Challenge® for pregnant or nursing women. If you are pregnant or nursing, please consult your physician to decide if an AdvoCare product regimen is appropriate for your needs.

  • At what age may I take AdvoCare® products?

    Please refer to the AdvoCare Product Age, Pregnancy and Nursing Indications document to see guidelines for product appropriateness. These guidelines are not intended as a substitute for the recommendation of your healthcare professional.

  • What is sucralose?

    Sucralose is a sweetener made from table sugar (sucrose) by chlorinating it in three positions on the molecule. This provides a substance which is approximately 600 times sweeter than sucrose and is very poorly absorbed. Therefore, the body does not metabolize it for energy, and only a small amount is needed to effectively sweeten a substance.

    Sucralose has the closest sweetness profile to sucrose, the “gold standard of sweeteners”. It also has exceedingly good solubility and stability properties, making it an excellent choice among non-nutritive sweeteners.

    Sucralose has over a twenty-year history of safe and effective use.* It carries no warning from the Food and Drug Administration (FDA) and is approved by the FDA as well as the World Health Organization Expert Committee on Food Additives. It is approved by food and health agencies of over 40 countries. It can be used by pregnant and nursing women since very little is absorbed. Thousands of food and beverage products around the world contain sucralose. AdvoCare® is not aware of any peer-reviewed human research studies published in reputable, well-recognized scientific journals demonstrating toxic or adverse effects.

    The scientific consensus of over 200 research articles affirms the safety of sucralose. The research studies which have been conducted to investigate the safety of sucralose have demonstrated no effects on organs, growth weight, blood chemistry or fertility, and sucralose is not carcinogenic, teratogenic or mutagenic. Sucralose does not produce diarrhea, affect the immune system, alter hormonal systems, cause headaches, produce fatigue or skin conditions. In well-controlled studies, no adverse effects have been found.

    The small amount of chlorine present on the sucrose molecule is a tiny fraction of the amount of chlorine already present in our stomachs in the form of hydrochloric acid which aids digestion. Furthermore, the amount of chlorine present is an even smaller fraction of the amount consumed daily in the form of table salt (sodium chloride).

    There are a number of prominent websites that contain extensive amounts of misinformation regarding sucralose and other substances. The information provided is not based on sound scientific studies. All of the information on these websites is anecdotal and has never been published in any reputable journal, does not involve any reputable research studies, and has never been demonstrated in research studies. Furthermore, the websites reference each other in an effort to create credibility.

    AdvoCare does not use products that are not demonstrated to be safe and well studied. AdvoCare does not use any ingredient deemed to be unsafe or harmful based on sound scientific evidence.

    *For more information on nonnutritive sweeteners, visit the links below.

    Safely Enjoy Sweetened Foods Within a Healthful Eating Plan

    Use of Nutritive and Nonnutritive Sweeteners

  • What sweeteners does AdvoCare® use in its products?

    There are approximately 30 sweeteners approved by the FDA for human consumption that are deemed to be safe and effective when used appropriately.

    The sweeteners used in AdvoCare® products are:
    i. Acesulfame potassium
    ii. Agave syrup
    iii. Corn syrup
    iv. Dextrose (glucose)
    v. Polydextrose
    vi. Fructose
    vii. High fructose corn syrup
    viii. Honey
    ix. Inulin/FOS
    x. Lactitol
    xi. Lactose
    xii. Maltitol/Maltitol syrup
    xiii. High maltose corn syrup
    xiv. Maltodextrin
    xv. Rice syrup
    xvi. Sucralose
    xvii. Sorbitol
    xviii. Sugar (sucrose)

  • What AdvoCare® products may be taken if someone has Inflammatory Bowel Disease (IBD)?

    Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition usually of unknown origin associated with impaired absorption of nutrients from the intestinal tract. Impaired absorption of nutrients is a common characteristic and symptoms may include altered bowel habits, abdominal pain, gas and flatulence. The two main forms of IBD are Crohn's Disease and ulcerative colitis.

    AdvoCare does not make medical claims regarding dietary supplements and does not treat medical conditions. Please consult your healthcare provider for determinations of product suitability. A number of AdvoCare products may be considered by the physician of an individual with IBD which may help support and maintain normal gastrointestinal health and aid in overall wellness.

  • Can AdvoCare® tablets be chewed or crushed if someone is unable to swallow them?

    Those with difficulty swallowing may chew or crush most AdvoCare caplets and tablets. One exception is ActoTherm SR, the thermogenic component in the first color packet of the MNS® 3 strip pack. Since the ActoTherm SR caplet is formulated using sustained-release technology, chewing or crushing the caplet interferes with the extended-release mechanism and results in more rapid release of the ingredients. Capsules may be opened and sprinkled on food.

    View the MNS 3 instructional flier for more information on ActoTherm SR.

  • Can you tell me why the Joint ProMotion™ formula does not contain chondroitin?

    Chondroitin and glucosamine are natural substances found in and around the cells of joint cartilage. According to the National Institutes of Health, researchers believe their presence in joints may help in the repair and maintenance of cartilage.

    Chondroitin is one of several glycosaminoglycans (GAGs) in joints. GAGs are the lubricants in synovial fluid, the fluid in the joint capsule that helps protect cartilage. Glucosamine is important in the production of hyaluronic acid, the main GAG in cartilage and a major GAG in synovial fluid. Glucosamine is made into chondroitin as an intermediary step in the production of GAGs. Chondroitin sulfate is a large macromolecule that must be broken down into glucosamine in order to be absorbed. As a consequence, there is no added benefit to using chondroitin as compared to glucosamine.